RT - Journal Article T1 - Factors affecting pregnancy and abortion rates following intra cytoplasmic sperm injection in the obstructive and non-obstructive azoospermic men JF - iau-tmuj YR - 2012 JO - iau-tmuj VO - 22 IS - 3 UR - http://tmuj.iautmu.ac.ir/article-1-594-en.html SP - 211 EP - 215 K1 - Obstructive azoosprmia K1 - Non obstructive azoospermia K1 - ICSI K1 - Clinical pregnancy rates AB - Background: Intracytoplasmic sperm injection (ICSI) has revolutionized the treatment of azoospermic men. The aim of this study was to evaluate the factors interfering in the success of ICSI, including sperm collection method, testicular histology, age and hormonal assay of the couple, the number of retrieved oocytes, and the number of transferred embryos. Materials and methods: In this retrospective cohort study, 246 azoospemic men (52 with obstructive azoosprmia (OA) and 194 with non obstructive azoospermia (NOA)) who were underwent sperm retrieval with PESA or TESE and ICSI protocol were studied. By long protocol of ovarian stimulation, oocytes were retrieved 36h after hCG administration. After 48h, cleaved embryos were replaced in the uterine cavity. Results: Clinical pregnancy rates (21.1% in OA versus 10.8% in NOA) was significantly correlated with sperm origin (P LA eng UL http://tmuj.iautmu.ac.ir/article-1-594-en.html M3 ER -