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Survey of serum fat-soluble vitamins, zinc, copper and selenium levels in patients with cystic fibrosis
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Soheila Khalilzadeh1   , Maryam Hassanzad 2, Mohammadreza Boloursaz3 , Sabereh Tashayoie Nejad3 , Nooshin Baghaie3 , Helenaz Fazlalizadeh3 , Ali Akbar Velayati4 |
1- Pediatric Pulmonologist, Pediatric Respiratory Diseases Research Center, NRITLD, Masih Daneshvari Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran
2- Pediatric Pulmonologist, Pediatric Respiratory Diseases Research Center, NRITLD, Masih Daneshvari Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran , pedlung.nritld@gmail.com
3- Pediatric Respiratory Diseases Research Center, NRITLD, Masih Daneshvari Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran
4- Chronic Respiratory Disease Research Center, NRITLD, Masih Daneshvari Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran |
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Abstract: (11307 Views) |
Background: Cystic fibrosis (CF) is a genetically disease with different respiratory and gastrointestinal organ involvement. Because of gastrointestinal tract involvement, patients have mal-absorption for vitamins and mineral elements for example vitamin A, D, E and trace elements such as Selenium (Se), Zinc (Zn) and Copper (Cu) have low serum level in CF patients in different studies. The goal of this study is to define relation between serum level of this elements and severity of respiratory and gastrointestinal tract involvement in these patients.
Materials and methods: This cross sectional study performed on 39 cystic fibrosis patients admitted in pediatric ward of Masih Daneshvari hospital, Tehran, Iran. Serum levels of Vitamin A, D and E, Selenium, Zinc and Copper deficiency were studied.
Results: Serum level of Vitamin A and D were lower than normal values. Also, 3 cases (7.68%) had serum level of Zinc lower than normal values.
Conclusion: CF patients are susceptible to have deficiencies of fat soluble vitamins and trace elements such as Selenium and Zinc because of mal-absorption. It seems that a perfect diet and nutritional components are helpful in prevention of these problems.
Keywords: Cystic fibrosis, Zinc, Copper, Selenium, Vitamin. |
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| Keywords: Cystic fibrosis, Zinc, Copper, Selenium, Vitamin. |
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Full-Text [PDF 287 kb]
(2056 Downloads)
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Semi-pilot: Survey/Cross Sectional/Descriptive |
Subject:
Pulmonary
Received: 2014/03/9 | Accepted: 2014/03/9 | Published: 2014/03/9
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