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:: Volume 22, Issue 1 (spring2012 2012) ::
MEDICAL SCIENCES 2012, 22(1): 39-43 Back to browse issues page
Efficacy of intra-cuff dexamethasone and magnesium sulphate on frequency and severity of post- intubation sore throat
Ladan Ansari * 1, Kaveh Roostaeeian 2, Katayun Ansari 3, Gholamreza Asgari 4
1- Department of Anesthesiology, Boo-Ali Hospital, Islamic Azad university, Tehran Medical Branch, Tehran, Iran , ladanansari46@gmail.com
2- Department of Anesthesiology, Boo-Ali Hospital, Islamic Azad university, Tehran Medical Branch, Tehran, Iran
3- Otorhinolaryngologist, Tehran University of Medical Sciences, Tehran, Iran
4- Homeopathic Physician, Shahid Beheshti University, Tehran, Iran
Abstract:   (12260 Views)
Background: Sore throat is a common problem after general anesthesia. This study compared the efficacy of intra-cuff dexamethasone, Magnesium Sulfate and placebo on sore throat.
Materials and methods: This was a randomized double blind clinical trial among 90 patients who underwent general anesthesia with tracheal intubation in Boo-Ali hospital in 2008. They were randomly assigned to receive either 16 mg of intra-cuff dexamethasone, or 50 milligram per kilogram of intra-cuff magnesium sulfate or intra-cuff air. The patients were evaluated after recovery, at the end of the day, and on the morning after surgery for sore throat and its severity, according to VAS. Statistic analysis was done by ANOVA and Chi-square tests.
Results: There was no significant difference between the incidence of sore throat after recovery, at the end of operation day, and on the morning after operation between three groups (P > 0.05), but there was significant reduction in sore throat severity in intra-cuff dexamethasone group on the day after operation (P < 0.05).
Conclusion: Using intra-cuff dexamethasone or intra-cuff magnesium sulfate are not effective methods in decreasing incidence of post intubation sore throat, but using intra-cuff dexamethaone decreases sore throat severity.
Keywords: Tracheal intubation, Sore throat, Dexamethasone, Magnesium sulfate
Full-Text [PDF 359 kb]   (1316 Downloads)    
Type of Study: Controlled/Randomized clinical trial | Subject: Anesthesiology
Received: 2012/04/3
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ansari L, Roostaeeian K, ansari K, Asgari G. Efficacy of intra-cuff dexamethasone and magnesium sulphate on frequency and severity of post- intubation sore throat. MEDICAL SCIENCES. 2012; 22 (1) :39-43
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Volume 22, Issue 1 (spring2012 2012) Back to browse issues page
فصلنامه علوم پزشکی دانشگاه آزاد اسلامی واحد پزشکی تهران Medical Science Journal of Islamic Azad Univesity - Tehran Medical Branch
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