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:: Volume 28, Issue 2 (winter 2018) ::
MEDICAL SCIENCES 2018, 28(2): 117-123 Back to browse issues page
The effect of cardiac rehabilitation on ApoA1 and ApoB in men with coronary heart disease (CHD) after coronary artery bypass graft (CABG)
Mohsen Jafari * 1, Amir Rashidlamir 2, Mostafa Dastani 3, Mehrdad Fathi 2, Seyed Emad Alavinya 4
1- Assistant Professor Exercise Physiology, Department of Sport Sciences, Shirvan Branch, Islamic Azad University, Shirvan, Iran , sport87mohsen@gmail.com
2- Associated Professor Exercise Physiology, Department of Exercise Physiology, Faculty of Sport Sciences, Ferdowsi University of Mashhad, Mashhad, Iran
3- Associated Professor Cardiovascular Medicine, Department of Cardiology, Mashhad University of Medical Sciences, Mashhad, Iran
4- Cardiac Rehabilitation Physician, Department of Sports Sciences, Neyshabur Branch, Islamic Azad University, Neyshabur, Iran
Abstract:   (299 Views)
Background: Cardiac rehabilitation is a branch of rehabilitation medicine dealing with optimizing physical function in patients with atherosclerosis after coronary artery bypass graft (CABG). The aim of this study was to investigate the effects of a period of cardiac rehabilitation on serum levels of apo-A1 and apo-B in middle aged men with myocardial infarction after CABG.
Materials and methods: Subjects were selected among middle aged men (50 to 60 years old) with CABG and assigned into two groups of control (n=10) and experimental (n=10). In experimental group, aerobic exercises (treadmill, cycle and hand ergometer) with the intensity of 11 to 13 on the (basis of burg scale) were performed during eight weeks under control of physician. Before and after the trainings, serum levels of ApoA1 and ApoB were measured by ELISA method.
Results: Analysis of data using paired samples T test showed no changes in weight, BMI, levels of apo-A1 and apo-B and apo-B to apo-A1 ratio in control group (P>0.05), but in experimental group weight, BMI, apo-B and apo-B to apo-A1 ratio significantly decreased and apo-A1 increased (P<0.05). On the basis of independent T-test results, changes of weight, BMI and ApoA1 were significantly differed between two groups (P<0.05).
Conclusion: Eight weeks cardiac rehabilitation, through reduction of apo-A1 and apo-B, can be effective in prevention of recurrent myocardial infarction and morbidity and mortality in middle aged men after CABG.
 
Keywords: Rehabilitation, Apolipoprotein A1, Apolipoprotein B, Coronary artery bypass.
Full-Text [PDF 239 kb]   (69 Downloads)    
Type of Study: Quazi-Experimental | Subject: Physiology
Received: 2017/09/17 | Accepted: 2017/12/17 | Published: 2018/06/19
References
1. Rashidlamir A, Saadatnia A, Ebrahimi-Atri A, Delphan M. Effect of Eight Weeks of Wrestling and Circuit Fitness Training on Apo Lipoprotein A-I and Lymphocyte Abca1 Gene Expression in Well-Trained Wrestlers. Int J Wrest Sci 2011;1:48-53. [DOI:10.1080/21615667.2011.10878931]
2. Ghorani V, Rashidlamir A, Farzanegi P. Effects of 6 Weeks of Aerobic Training and Fenugreek Extract Administration on Plasma Apo A-I of Female Patients with Type 2 Diabetes. Ir J Health Phys Act 2014;5:29-34.
3. Dergunov AD. A mechanistic model of lecithin:cholesterol acyltransferase activity exploits discoidal HDL composition and structure. Arch Biochem Biophys 2012;520:81-7. [DOI:10.1016/j.abb.2012.02.006]
4. Yu HH, Ginsburg GS, O'Toole ML, Otvos JD, Douglas PS, Rifai N. Acute Changes in Serum Lipids and Lipoprotein Subclasses in Triathletes as Assessed by Proton Nuclear Magnetic Resonance Spectroscopy. Arterioscler Thromb Vasc Biol 1999;19:1945-9. [DOI:10.1161/01.ATV.19.8.1945]
5. Mann S, Beedie C, Jimenez A. Differential Effects of Aerobic Exercise, Resistance Training and Combined Exercise Modalities on Cholesterol and the Lipid Profile: Review, Synthesis and Recommendations. Sports Med 2013;44:211-21. [DOI:10.1007/s40279-013-0110-5]
6. Safarzade A, Rohi H, Fathi R, Talebi-Garakani E. Effect of progressive resistance training on serum amyloid A and apolipoprotein A-I levels in diabetic Rats. Koomesh 2013;15:22-30. (Persian)
7. Holme I, Hostmark AT, Anderssen SA. ApoB but not LDL-cholesterol is reduced by exercise training in overweight healthy men. Results from the 1-year randomized Oslo Diet and Exercise Study. J Intern Med 2007;262:235-43. [DOI:10.1111/j.1365-2796.2007.01806.x]
8. Couillard C, Despres JP, Lamarche B, Bergeron J, Gagnon J, Leon AS, et al. Effects of Endurance Exercise Training on Plasma HDL Cholesterol Levels Depend on Levels of Triglycerides Evidence From Men of the Health, Risk Factors, Exercise Training and Genetics (HERITAGE) Family Study. Arterioscler Thromb Vasc Biol 2001;21:1226-32. [DOI:10.1161/hq0701.092137]
9. Liem AH, Jukema JW, Van Veldhuisen DJ. Secondary prevention in coronary heart disease patients with low HDL: which options do we have? Int J Cardiol 2003;90:15-21. [DOI:10.1016/S0167-5273(02)00515-6]
10. Takashima A, Ise T, Yagi S, Iwase T, Kimura S, Ueda Y, et al. Cardiac Rehabilitation Reduces Serum Levels of Oxidized Low-Density Lipoprotein. Circ J 2014;78:2682-7. [DOI:10.1253/circj.CJ-14-0532]
11. Nalini M, Najafi F, Saeidi M, Gerami F, Ashraf Rashidi A, Ezzati P. Changes in exercise capacity and modifiable risk factors after a comprehensive cardiac rehabilitation in patients with and without left ventricular systolic dysfunction. Behbood 2009;13:184-96. (Persian)
12. Afzalaghaiee E, Hadian M, Attarbashi Moghadam B, Tavakol K, Zandparsa A, Jalaei S, et al . The Effects Of Cardiac Rehabilitation On Changes In The Lipid Profile Of Iranian male and female With Coronary Artery Disease Refered To Emam Khomeini Hospital Complex. MRJ 2010;4:45-9. (Persian)
13. Back M, Cider A, Gillstrom J, Herlitz J. Physical activity in relation to cardiac risk markers in secondary prevention of coronary artery disease. Int J Cardiol 2012;168:478-83. [DOI:10.1016/j.ijcard.2012.09.117]
14. Kubilius R, Jasiukeviciene L, Grizas V, Kubiliene L, Jakubseviciene E, Vasiliauskas D. The Impact of Complex Cardiac Rehabilitation on Manifestation of Risk Factors in patients with Coronary Heart Disease. Medicina (Kaunas) 2012;48:166-73. [DOI:10.3390/medicina48030024]
15. Abdi M, Marefati H, Moazenzadeh M. The effect of cardiac rehabilitation on the serum levels of adiponectin and lipoproteins in male atherosclerotic patients. J Kerman Univ Med Sci 2012;19:317-25. (Persian)
16. Milani RV, Lavie CJ, Mehra MR. Reduction in C - reactive protein Through Cardiac Rehabilitation and Exercise Training. J Am Col Cardiol 2004;43:1056-61. [DOI:10.1016/j.jacc.2003.10.041]
17. Gayda M, Brun C, Juneau M, Levesque S, Nigam A. Long term cardiac rehabilitation and exercise training programs improve metabolic parameters in metabolic syndrome patients with and without coronary heart disease. Nutr Metab Cardiovasc Dis 2008;18:142-51. [DOI:10.1016/j.numecd.2006.07.003]
18. Pluss CE, Karlsson MR, Wallen NH, Billing E, Held C. Effects of an expanded cardiac rehabilitation programme in patients treated for an acute myocardial infarction or a coronary artery by-pass graft operation. Clin Rehab 2008;22:306-18. [DOI:10.1177/0269215507085379]
19. Glass CK, Witztum JL. Atherosclerosis: The Road Ahead. Cell 2001;104:503-16. [DOI:10.1016/S0092-8674(01)00238-0]
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Jafari M, Rashidlamir A, Dastani M, Fathi M, Alavinya S E. The effect of cardiac rehabilitation on ApoA1 and ApoB in men with coronary heart disease (CHD) after coronary artery bypass graft (CABG) . MEDICAL SCIENCES. 2018; 28 (2) :117-123
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Volume 28, Issue 2 (winter 2018) Back to browse issues page
فصلنامه علوم پزشکی دانشگاه آزاد اسلامی واحد پزشکی تهران Medical Science Journal of Islamic Azad Univesity - Tehran Medical Branch
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