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:: Volume 28, Issue 2 (winter 2018) ::
MEDICAL SCIENCES 2018, 28(2): 117-123 Back to browse issues page
The effect of cardiac rehabilitation on ApoA1 and ApoB in men with coronary heart disease (CHD) after coronary artery bypass graft (CABG)
Mohsen Jafari 1, Amir Rashidlamir2 , Mostafa Dastani3 , Mehrdad Fathi2 , Seyed Emad Alavinya4
1- Exercise Physiology, Department of Sport Sciences, Shirvan Branch, Islamic Azad University, Shirvan, Iran , sport87mohsen@gmail.com
2- Exercise Physiology, Department of Exercise Physiology, Faculty of Sport Sciences, Ferdowsi University of Mashhad, Mashhad, Iran
3- Cardiovascular Medicine, Department of Cardiology, Mashhad University of Medical Sciences, Mashhad, Iran
4- Cardiac Rehabilitation Physician, Department of Sports Sciences, Neyshabur Branch, Islamic Azad University, Neyshabur, Iran
Abstract:   (4697 Views)
Background: Cardiac rehabilitation is a branch of rehabilitation medicine dealing with optimizing physical function in patients with atherosclerosis after coronary artery bypass graft (CABG). The aim of this study was to investigate the effects of a period of cardiac rehabilitation on serum levels of apo-A1 and apo-B in middle aged men with myocardial infarction after CABG.
Materials and methods: Subjects were selected among middle aged men (50 to 60 years old) with CABG and assigned into two groups of control (n=10) and experimental (n=10). In experimental group, aerobic exercises (treadmill, cycle and hand ergometer) with the intensity of 11 to 13 on the (basis of burg scale) were performed during eight weeks under control of physician. Before and after the trainings, serum levels of ApoA1 and ApoB were measured by ELISA method.
Results: Analysis of data using paired samples T test showed no changes in weight, BMI, levels of apo-A1 and apo-B and apo-B to apo-A1 ratio in control group (P>0.05), but in experimental group weight, BMI, apo-B and apo-B to apo-A1 ratio significantly decreased and apo-A1 increased (P<0.05). On the basis of independent T-test results, changes of weight, BMI and ApoA1 were significantly differed between two groups (P<0.05).
Conclusion: Eight weeks cardiac rehabilitation, through reduction of apo-A1 and apo-B, can be effective in prevention of recurrent myocardial infarction and morbidity and mortality in middle aged men after CABG.
 
Keywords: Rehabilitation, Apolipoprotein A1, Apolipoprotein B, Coronary artery bypass.
Full-Text [PDF 210 kb]   (1420 Downloads)    
Semi-pilot: Quazi-Experimental | Subject: Physiology
Received: 2017/09/17 | Accepted: 2017/12/17 | Published: 2018/06/19
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Jafari M, Rashidlamir A, Dastani M, Fathi M, Alavinya S E. The effect of cardiac rehabilitation on ApoA1 and ApoB in men with coronary heart disease (CHD) after coronary artery bypass graft (CABG) . MEDICAL SCIENCES 2018; 28 (2) :117-123
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Volume 28, Issue 2 (winter 2018) Back to browse issues page
فصلنامه علوم پزشکی دانشگاه آزاد اسلامی واحد پزشکی تهران Medical Science Journal of Islamic Azad Univesity - Tehran Medical Branch
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