:: Volume 27, Issue 4 (winter 2017) ::
MEDICAL SCIENCES 2017, 27(4): 261-268 Back to browse issues page
The effect of combined training on body composition, and ccoagulation and proinflammatory factors in overweight and obese postmenopausal women
Ramin Shabani *
Associate Professor Department of Physical Education and Sport Sciences, Rasht branch, Islamic Azad University, Rasht, Guilan, Iran , dr.ramin.shabani@gmail.com
Abstract:   (1166 Views)
Background: Research suggests that the decline in ovarian function with menopause is associated with spontaneous increases in pro inflammatory and coagulation factors. The aim of this study was to determine the effect of combined training on body composition, and inflammatory and coagulation factors in overweight and obese postmenopausal women.
Materials and methods: In this quasi experimental study, a total of twenty-six apparently health postmenopausal women were randomly assigned to an endurance resistance exercise (n = 13) or control group (n = 13). The exercise group trained 90 minute, three times per week for 8 weeks. The control group did not train. End points included changes in weight, body mass index (BMI), waist-to-hip ratio (WHR), and serum high sensitive C-reactive protein (hs-CRP), interleukin 6 (IL-6), and plasma fibrinogen between baseline and 8-th week. Data were analyzed by paired and independent t test. P-value<0.05 was considered significant.
Results: Twenty-two participants completed the trial. At baseline, there were no significant differences in study variables between control and exercise groups. Exercise training significantly reduced weight, BMI, and WHR (p=0.001). Also exercise training decreased plasma levels of hs-CRP and IL-6 (p=0.001), and fibrinogen (p=0.01) in experimental group. While the control group showed no significant changes during this period.
Conclusion: Our study showed that exercise training is effective in reducing body composition and inflammatory and coagulation factors in overweight and obese postmenopausal women. So, Our results suggest that an endurance-resistance exercise program can improve health status of postmenopausal women.
Keywords: Exercise training, Inflammatory factors, Menopause, Fibrinogen
Full-Text [PDF 245 kb]   (168 Downloads)    
Type of Study: Experimental | Subject: Molecular Biology
Received: 2017/01/11 | Accepted: 2017/05/6 | Published: 2017/12/23


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Volume 27, Issue 4 (winter 2017) Back to browse issues page