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Assessment of factors affecting kidney transplant survival based on literature review between 2000 and 2014
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Reza Rabiei1   , Hamid Moghaddasi2 , Ali Akbar Khadem Maboudi2 , Abbas Basiri3 , Shahabedin Rahmatizadeh 4 |
1- Department of Health Information Technology and Management, School of Allied Medical Sciences, Shahid Beheshti University of Medical Sciences, Tehran, Iran
2- Department of Biostatistics, School of Allied Medical Sciences, Shahid Beheshti University of Medical Sciences, Tehran, Iran
3- Department of Urology, Urology and Nephrology Research Center, Shahid Labbafinejad Medical Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran
4- Department of Health Information Technology and Management, School of Allied Medical Sciences, Shahid Beheshti University of Medical Sciences, Tehran, Iran , sh.rahmatizadeh@sbmu.ac.ir |
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Abstract: (4737 Views) |
| Background: Improvements in immune-suppressing drugs have a short-term effect on kidney transplants but do not have much long-term effect. In order to increase the duration of kidney transplant survival, understanding the significant parameters is of great importance. This study aims to identify key parameters (before the transplant occurs) which affect kidney transplant survival.
Materials and methods: To conduct this review, the scientific databases was searched and more than 200 related titles were retrieved; and the abstracts were reviewed to determine which studies were relevant to the study. The literature analysis was based on the goals of the studies themselves, the number of citations, and the reliability of the sources cited. Ultimately, 60 studies included for further analysis.
Results: Based on the frequency of each parameter which influenced graft survival, the following parameters were determined to have higher frequencies compared to other parameters, with regards to survival time of the kidney transplant: the ages of the donor and recipient, socioeconomic status, immune-suppressing drugs, HLA matching, time on the waiting list, live or deceased donor, the decade in which the operation occurred, cold ischemia time, and reaction to antibiotics.
Conclusion: The influence of some of the kidney transplant survival parameters was acknowledged in the majority of studies; however, some parameters have been the subject of disagreement among studies. In order to resolve this issue, we suggest a search of international data and meta-analysis of current literature to better understand the parameters of kidney transplant survival.
Keywords: Kidney transplant, Kidney transplant survival, Factors affecting kidney transplant survival. |
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| Keywords: Kidney transplant, Kidney transplant survival, Factors affecting kidney transplant survival. |
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Full-Text [PDF 203 kb]
(1234 Downloads)
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Semi-pilot: Review |
Subject:
Urology
Received: 2016/11/29 | Accepted: 2017/04/16 | Published: 2017/06/19
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