[Home ] [Archive]   [ فارسی ]  
:: Main :: About :: Current Issue :: Archive :: Search :: Submit :: Contact ::
:: Volume 27, Number 1 (spring 2017) ::
MEDICAL SCIENCES 2017, 27(1): 9-16 Back to browse issues page
Effects of Avicennia marina fruits aqueous and hydro alcoholic extract on streptozotosin –induced diabetic male rats
Liela Kamaei *1, Hadi Fathi Moghaddam2, Mokhtar Mokhtari3, Seyyed Ali Mard2, Davood Moghadamnia, Davood Moghadamnia
1- , Leila.Kamaei@yahoo.com
2- Associated Professor
3- Professor
Abstract:   (702 Views)
Background: Diabetes mellitus is a major endocrine disorder and growing health problem in most countries. We studied effects of Avicennia marina fruits aqueous and hydroalcoholic extract in the diabetic rat by streptozotocin. Materials and methods: In this experimental study, 45 male rats were divided into 9 groups of 5, including sham group, diabetes sham, positive sham (diabetes + 0.9% normal saline) and treated diabetic groups orally with aqueous and hydroalcoholic extract of Avicennia marina fruits (30, 60, 120 mg/kg daily for three consecutive days). Twenty-four hours after the last treatment rats, blood samples were collected from heart for determining the blood glucose and insulin concentration levels using glucose oxidase and enzyme-linked immunosorbent assay (ELISA) methods respectively. Results: All doses of Avicennia marina fruits aqueous and hydroalcoholic extract significantly decreased serum glucose level of diabetic test rats compared to treated diabetic sham rats. 60mg/kg of Avicennia marina fruits hydroalcoholic extract and all doses of Avicennia marina fruits aqueous extract significantly increased serum insulin level of diabetic test rats compared to treated diabetic sham rats. Conclusion: In this study, we have shown that Avicennia marina fruits aqueous and hydroalcoholic extract can significantly decrease the blood glucose. Keywords: Avicennia marina, Diabete, Blood glucose, Insulin.
Keywords: Avicennia marina, Diabete, Blood glucose, Insulin.
Full-Text [PDF 269 kb]   (392 Downloads)    
Type of Study: Experimental | Subject: Physiology
Received: 2016/07/6 | Accepted: 2016/09/13 | Published: 2017/04/1
Send email to the article author

Add your comments about this article
Your username or email:

Write the security code in the box >



XML   Persian Abstract   Print


Download citation:
BibTeX | RIS | EndNote | Medlars | ProCite | Reference Manager | RefWorks
Send citation to:

Kamaei L, Fathi Moghaddam H, Mokhtari M, Mard S A, Moghadamnia D, Moghadamnia D. Effects of Avicennia marina fruits aqueous and hydro alcoholic extract on streptozotosin –induced diabetic male rats. MEDICAL SCIENCES. 2017; 27 (1) :9-16
URL: http://iau-tmuj.ir/article-1-1212-en.html
Volume 27, Number 1 (spring 2017) Back to browse issues page
فصلنامه علوم پزشکی دانشگاه آزاد اسلامی واحد پزشکی تهران Medical Science Journal of Islamic Azad Univesity - Tehran Medical Branch
Persian site map - English site map - Created in 0.049 seconds with 795 queries by yektaweb 3461