[Home ] [Archive]   [ فارسی ]  
:: Main :: About :: Current Issue :: Archive :: Search :: Submit :: Contact ::
Main Menu
Home::
Journal Information::
Articles archive::
For Authors::
For Reviewers::
Registration::
Contact us::
Site Facilities::
Webmail::
::
Search in website

Advanced Search
..
Receive site information
Enter your Email in the following box to receive the site news and information.
..
:: Volume 17, Issue 2 (Summer 2007) ::
MEDICAL SCIENCES 2007, 17(2): 65-73 Back to browse issues page
Study of aspergillosis risk factors in high risk patients
Shahindokht Basiri Jahromi 1, Aliasghar Khaksar
1- , basiri@pasteur.ac.ir
Abstract:   (18449 Views)
Background: Invasive aspergillosis (IA) is a major opportunistic infection in immunocompromised patients. Aspergillus is the main cause of mortality due to infection after transplantation and remains a major complication in hematologic malignancies. Despite considerable progresses in infection management, aspergillosis remains an important cause of morbidity and mortality, mainly after transplantation.
Materials and methods: During an 11-year period (April 1996 to March 2006), a retrospective study was achieved on 24 patients with aspergillosis in order to identify significant risk factors for invasive aspergillosis. Diagnosis was confirmed by demonstration of fungi in direct preparation and culture techniques.
 Results: Aspergillosis was more commonly isolated from respiratory tract (75%). Patients had at least one predisposing factor for aspergillosis. Among patients with solid organ transplantation, kidney transplant patients and chronic granulomatos disease were at the higher risk of developing invasive aspergillosis (IA).
 Conclusion: Major advances in management of invasive fungal infections (IFI) have resulted from our understanding of the risk factors for the development of IFI. However, much remains to be done to decrease mortality due to IFI in high risk patients. A high degree of awareness and efforts for an early diagnosis may improve poor prognosis. This study signifies that clinicians should be alerted of potential fungal etiology in cases of fever, which is unresponsive to conventional medical therapy.
Keywords: Aspergillosis, Risk factors, Fungal infections, Immunocompromised patients.
Full-Text [PDF 289 kb]   (3559 Downloads)    
Subject: Epidemiology
Received: 2006/09/6 | Published: 2007/06/15
Send email to the article author

Add your comments about this article
Your username or Email:

CAPTCHA


XML   Persian Abstract   Print


Download citation:
BibTeX | RIS | EndNote | Medlars | ProCite | Reference Manager | RefWorks
Send citation to:

Basiri Jahromi S, Khaksar A. Study of aspergillosis risk factors in high risk patients . MEDICAL SCIENCES 2007; 17 (2) :65-73
URL: http://tmuj.iautmu.ac.ir/article-1-75-en.html


Rights and permissions
Creative Commons License This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.
Volume 17, Issue 2 (Summer 2007) Back to browse issues page
فصلنامه علوم پزشکی دانشگاه آزاد اسلامی واحد پزشکی تهران Medical Science Journal of Islamic Azad Univesity - Tehran Medical Branch
Persian site map - English site map - Created in 0.05 seconds with 37 queries by YEKTAWEB 4645