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Comparison of two antimicrobial susceptibility tests, disk diffusion and E-test for determining oxacillin and vancomycin susceptibility
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Zohreh Maleki   1, Soghra Anjarani |
| 1- , zohrehmaleki2000@yahoo.com |
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Abstract: (16378 Views) |
Background: Staphylococcus aureus (S. aureus) is an important cause of nosocomial infections while recently resistance to oxacillin and vancomycin have been noted in literature.
Materials and methods: We studied 100 isolates of S. aureus from Emam Khomeini hospital by two antimicrobial susceptibility tests (AST) disk diffusion test (DDT) and E-test to determine the resistance to oxacillin (according to NCCLS comment) and vancomycin.
Results: There were no resistant S. aureus to vancomycin neither in DDT nor in E-test, however, there were 42% oxacillin-resistance S. aureus in both techniques. The results showed high prevalence of methicillin-resistant Staphylococcus aureus (MRSA) in Emam Khomeini hospital. The highest S. aureus infection detected from internal wards (26%), heart surgery ward (23%), sampling sites in wound (26%), surgical incision (20%), blood culture (17%) and prosthetic sites (14%).
Conclusion: We should pay further attention to high risk wards and sites to control hospital infections. According to our results, there was a high coincidence between two AST methods. |
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| Keywords: Staphylococcus aureus, Disk diffusion test, E-test. |
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Full-Text [PDF 158 kb]
(3306 Downloads)
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Subject:
Epidemiology
Received: 2006/09/6 | Published: 2006/12/15
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